Journal of Wound Medicine Journal of Wound Medicine 1 2 2026-03-01 Navneet O Soni Navneet O Soni navneetsoni1978@yahoo.com 1 10 10.5281/zenodo.18844419 https://doi.org/10.5281/zenodo.18844419 https://journalofwoundmedicine.in/article-2026-02-soni.html https://journalofwoundmedicine.in/journal/soni-2026-review.pdf Zenodo https://doi.org/10.5281/zenodo.18844419 To thoroughly assess the various animal and experimental wound models used in wound healing research, this systematic review summarizes the species, strains, advantages, limitations, and methodological considerations for selecting appropriate models. Databases including PubMed, Scopus, Web of Science, and Google Scholar were searched until December 2025. Eight major animal species and eight commonly used wound models were identified. The selection of models should align with the research objective and clinical relevance. Wound healing Animal wound models Full-thickness wound model Excision wound model Incision wound model Burn injury model Diabetic wound model Soni, N. (2026). Species-Specific and Wound-Specific Models in Preclinical Wound Healing: A Comprehensive Review. Journal of Wound Medicine, 1(2), 1–10. https://doi.org/10.5281/zenodo.18844419 en Review Article